Rumor has it that on the third floor of Kamome Academy's old building, there exists the spirit of a young girl named Hanako-san in the girls' restroom. It is said that whoever summons Hanako-san is granted any wish they desire. When high school first-year Nene Yashiro discovers her boyfriend's disloyalty, she decides to call upon Hanako-san to enact revenge. To Yashiro's surprise, she comes face to face with a boy instead of a girl!

Hanako-kun, bored out of his mind, is delighted to see someone enter. As the third-generation Hanako-san of the Toilet, it is his responsibility to watch over the students of the school—and that includes fulfilling their wishes. However, nothing can be done until someone summons him.

Thus, the meeting between a human and a ghost marks the beginning of a curious relationship.

Included one-shot: Itoshi no Living Dead (My Dear Living Dead)