Twenty years ago, the fascist government of the Republic of Greater East Asia seized control of Japan. In order to terrorize the citizens and crush any possibility of rebellion, the government set up Program 68, a savage military program where Japanese high school students were sent to a remote island and forced to kill each other—the Battle Royale.

After being banned for two decades, Program 68 is back, now under the direction of a sinister government artificial intelligence. The troubled and misbehaving kids of Daitoa Academy's Class F have been chosen, armed, and divided into squads, and now must fight each other to the death. Friendships and loyalties will be tested, and only the strongest will survive.