High school students by day and contract killers by night, Bullet and Francesca are knees deep in the underworld. The combination of close quarters and marksman fighting styles makes them a duo to be reckoned with.

Explosive marksman Lucia "Bullet" Ishikawa and dual axe-wielding psycho Maine "Francesca" Shirato both work under Minoko Konomi, the boss of the Kanto Iwashi family, who also happens to be a high school girl. Following Minoko's orders, the duo completes their assignments without a hitch.

Their missions put them in constant contact with the trash of society: thugs, serial killers, criminal kingpins, rapists, and assassins. Every time, Bullet and Francesca deal with them in the messiest of ways—in a maelstrom of guts, blood, and flesh.